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Use of LC-MS/MS to Identify Matrilysin/Matrix Metalloproteinase-7(MMP7) Cleavage Products of Perlecan (PLN)/Heparan Sulfate Proteoglycan (HSPG2)
Introduction: PLN/HSPG2, a 450 KDa heparan sulfate (HS) proteoglycan, is expressed in the basement membrane (BM) underlying epithelial and endothelial cells. Break down of PLN and other BM proteins is thought to play a critical role in prostate cancer (PCa) metastasis. During PCa metastasis, a varie...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Association of Biomolecular Resource Facilities
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635252/ |
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