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Inhibition of Nuclear Pore Complex Formation Selectively Induces Cancer Cell Death

Nuclear pore complexes (NPCs) are the central mediators of nucleocytoplasmic transport. Increasing evidence shows that many cancer cells have increased numbers of NPCs and become addicted to the nuclear transport machinery. How reducing NPC numbers affects the physiology of normal and cancer cells a...

詳細記述

保存先:
書誌詳細
出版年:Cancer Discov
主要な著者: Sakuma, Stephen, Raices, Marcela, Borlido, Joana, Guglielmi, Valeria, Zhu, Ethan Y.S., D’Angelo, Maximiliano A.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004544/
https://ncbi.nlm.nih.gov/pubmed/32988961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0581
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