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Inhibition of Nuclear Pore Complex Formation Selectively Induces Cancer Cell Death

Nuclear pore complexes (NPCs) are the central mediators of nucleocytoplasmic transport. Increasing evidence shows that many cancer cells have increased numbers of NPCs and become addicted to the nuclear transport machinery. How reducing NPC numbers affects the physiology of normal and cancer cells a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Discov
Egile Nagusiak: Sakuma, Stephen, Raices, Marcela, Borlido, Joana, Guglielmi, Valeria, Zhu, Ethan Y.S., D’Angelo, Maximiliano A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004544/
https://ncbi.nlm.nih.gov/pubmed/32988961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0581
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