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Inhibition of Nuclear Pore Complex Formation Selectively Induces Cancer Cell Death

Nuclear pore complexes (NPCs) are the central mediators of nucleocytoplasmic transport. Increasing evidence shows that many cancer cells have increased numbers of NPCs and become addicted to the nuclear transport machinery. How reducing NPC numbers affects the physiology of normal and cancer cells a...

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Bibliografske podrobnosti
izdano v:Cancer Discov
Main Authors: Sakuma, Stephen, Raices, Marcela, Borlido, Joana, Guglielmi, Valeria, Zhu, Ethan Y.S., D’Angelo, Maximiliano A.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004544/
https://ncbi.nlm.nih.gov/pubmed/32988961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0581
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