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Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model

The human RNase3 is a member of the RNaseA superfamily involved in host immunity. RNase3 is expressed by leukocytes and shows broad-spectrum antimicrobial activity. Together with a direct antimicrobial action, RNase3 exhibits immunomodulatory properties. Here, we have analysed the transcriptome of m...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Lu, Lu, Wei, RanLei, Prats-Ejarque, Guillem, Goetz, Maria, Wang, Gang, Torrent, Marc, Boix, Ester
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004517/
https://ncbi.nlm.nih.gov/pubmed/33226440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03695-5
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