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Evolutionary Trends in RNA Base Selectivity Within the RNase A Superfamily

There is a growing interest in the pharmaceutical industry to design novel tailored drugs for RNA targeting. The vertebrate-specific RNase A superfamily is nowadays one of the best characterized family of enzymes and comprises proteins involved in host defense with specific cytotoxic and immune-modu...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Prats-Ejarque, Guillem, Lu, Lu, Salazar, Vivian A., Moussaoui, Mohammed, Boix, Ester
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794472/
https://ncbi.nlm.nih.gov/pubmed/31649540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01170
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