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Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation

Human Ribonuclease 6 is a secreted protein belonging to the ribonuclease A (RNaseA) superfamily, a vertebrate specific family suggested to arise with an ancestral host defense role. Tissue distribution analysis revealed its expression in innate cell types, showing abundance in monocytes and neutroph...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Pulido, David, Arranz-Trullén, Javier, Prats-Ejarque, Guillem, Velázquez, Diego, Torrent, Marc, Moussaoui, Mohammed, Boix, Ester
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849008/
https://ncbi.nlm.nih.gov/pubmed/27089320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040552
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