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The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement
Human RNase 6 is a cationic secreted protein that belongs to the RNase A superfamily. Its expression is induced in neutrophils and monocytes upon bacterial infection, suggesting a role in host defence. We present here the crystal structure of RNase 6 obtained at 1.72 Å (1 Å=0.1 nm) resolution, which...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888456/ https://ncbi.nlm.nih.gov/pubmed/27013146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160245 |
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