Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial

BACKGROUND: Oxidative stress (OxS) and mitochondrial dysfunction are implicated as causative factors for aging. Older adults (OAs) have an increased prevalence of elevated OxS, impaired mitochondrial fuel‐oxidation (MFO), elevated inflammation, endothelial dysfunction, insulin resistance, cognitive...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Kumar, Premranjan, Liu, Chun, Hsu, Jean W., Chacko, Shaji, Minard, Charles, Jahoor, Farook, Sekhar, Rajagopal V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002905/
https://ncbi.nlm.nih.gov/pubmed/33783984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.372
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