Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial

BACKGROUND: Oxidative stress (OxS) and mitochondrial dysfunction are implicated as causative factors for aging. Older adults (OAs) have an increased prevalence of elevated OxS, impaired mitochondrial fuel‐oxidation (MFO), elevated inflammation, endothelial dysfunction, insulin resistance, cognitive...

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Veröffentlicht in:Clin Transl Med
Hauptverfasser: Kumar, Premranjan, Liu, Chun, Hsu, Jean W., Chacko, Shaji, Minard, Charles, Jahoor, Farook, Sekhar, Rajagopal V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002905/
https://ncbi.nlm.nih.gov/pubmed/33783984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.372
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