CORRECTING GLUTATHIONE DEFICIENCY AND MITOCHONDRIAL DYSFUNCTION IN OLDER HUMANS: A RANDOMIZED CLINICAL TRIAL

Aging is associated with impaired mitochondrial fatty-acid oxidation (MFO) due to unknown mechanisms, and interventions are lacking. We hypothesized that impaired MFO in aging occurs due to Glutathione-deficiency and tested this in a randomized, placebo-controlled double-blind clinical-trial in 24 o...

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Bibliografske podrobnosti
izdano v:Innov Aging
Main Authors: Sekhar, Rajagopal V, Kumar, Premranjan, Hsu, Jean W, Suliburk, James, Taffet, George E, Minard, Charles G, Jahoor, Farook, Liu, Chun
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Session 2190 (Symposium)
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6840014/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.1552
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