Supplementing Glycine and N-acetylcysteine (GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an Open-Label Clinical Trial

Background: Patients with HIV (PWH) develop geriatric comorbidities, including functional and cognitive decline at a younger age. However, contributing mechanisms are unclear and interventions are lacking. We hypothesized that deficiency of the antioxidant protein glutathione (GSH) contributes to mu...

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Veröffentlicht in:Biomedicines
Hauptverfasser: Kumar, Premranjan, Liu, Chun, Suliburk, James W., Minard, Charles G., Muthupillai, Raja, Chacko, Shaji, Hsu, Jean W., Jahoor, Farook, Sekhar, Rajagopal V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601820/
https://ncbi.nlm.nih.gov/pubmed/33007928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100390
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