Metabolic and Mitochondrial Functioning in Chimeric Antigen Receptor (CAR)—T Cells

SIMPLE SUMMARY: We review the mechanisms of cellular metabolism and mitochondrial function that have potential to impact on the success of chimeric antigen receptor (CAR) T cell therapy. The review focuses readers on mitochondrial functions to allow a better understanding of the complexity of T cell...

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Publicado en:Cancers (Basel)
Main Authors: Rad S. M., Ali Hosseini, Halpin, Joshua Colin, Mollaei, Mojtaba, Smith Bell, Samuel W. J., Hirankarn, Nattiya, McLellan, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002030/
https://ncbi.nlm.nih.gov/pubmed/33799768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061229
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