High Prevalence of Insulin Resistance in Asymptomatic Patients with Acute Intermittent Porphyria and Liver-Targeted Insulin as a Novel Therapeutic Approach

Acute porphyria attacks are associated with the strong up-regulation of hepatic heme synthesis and over-production of neurotoxic heme precursors. First-line therapy is based on carbohydrate loading. However, altered glucose homeostasis could affect its efficacy. Our first aim was to investigate the...

Full description

Saved in:
Bibliographic Details
Published in:Biomedicines
Main Authors: Solares, Isabel, Izquierdo-Sánchez, Laura, Morales-Conejo, Montserrat, Jericó, Daniel, Castelbón, Francisco Javier, Córdoba, Karol Marcela, Sampedro, Ana, Lumbreras, Carlos, Moreno-Aliaga, María Jesús, Enríquez de Salamanca, Rafael, Berraondo, Pedro, Fontanellas, Antonio
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002016/
https://ncbi.nlm.nih.gov/pubmed/33807619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9030255
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items