High Prevalence of Insulin Resistance in Asymptomatic Patients with Acute Intermittent Porphyria and Liver-Targeted Insulin as a Novel Therapeutic Approach

Acute porphyria attacks are associated with the strong up-regulation of hepatic heme synthesis and over-production of neurotoxic heme precursors. First-line therapy is based on carbohydrate loading. However, altered glucose homeostasis could affect its efficacy. Our first aim was to investigate the...

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Pubblicato in:Biomedicines
Autori principali: Solares, Isabel, Izquierdo-Sánchez, Laura, Morales-Conejo, Montserrat, Jericó, Daniel, Castelbón, Francisco Javier, Córdoba, Karol Marcela, Sampedro, Ana, Lumbreras, Carlos, Moreno-Aliaga, María Jesús, Enríquez de Salamanca, Rafael, Berraondo, Pedro, Fontanellas, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002016/
https://ncbi.nlm.nih.gov/pubmed/33807619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9030255
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