Renal Failure Affects the Enzymatic Activities of the Three First Steps in Hepatic Heme Biosynthesis in the Acute Intermittent Porphyria Mouse

Chronic kidney disease is a long-term complication in acute intermittent porphyria (AIP). The pathophysiological significance of hepatic overproduction of the porphyrin precursors aminolevulinate acid (ALA) and porphobilinogen (PBG) in chronic kidney disease is unclear. We have investigated the effe...

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Autori principali: Unzu, Carmen, Sampedro, Ana, Sardh, Eliane, Mauleón, Itsaso, Enríquez de Salamanca, Rafael, Prieto, Jesús, Salido, Eduardo, Harper, Pauline, Fontanellas, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295788/
https://ncbi.nlm.nih.gov/pubmed/22412963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032978
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