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Renal Failure Affects the Enzymatic Activities of the Three First Steps in Hepatic Heme Biosynthesis in the Acute Intermittent Porphyria Mouse

Chronic kidney disease is a long-term complication in acute intermittent porphyria (AIP). The pathophysiological significance of hepatic overproduction of the porphyrin precursors aminolevulinate acid (ALA) and porphobilinogen (PBG) in chronic kidney disease is unclear. We have investigated the effe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Unzu, Carmen, Sampedro, Ana, Sardh, Eliane, Mauleón, Itsaso, Enríquez de Salamanca, Rafael, Prieto, Jesús, Salido, Eduardo, Harper, Pauline, Fontanellas, Antonio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295788/
https://ncbi.nlm.nih.gov/pubmed/22412963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032978
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