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Inhibition of NUPR1–Karyopherin β1 Binding Increases Anticancer Drug Sensitivity

Background: Nuclear protein-1 (NUPR1, also known as p8/Com-1) is a transcription factor involved in the regulation of cellular stress responses, including serum starvation and drug stimulation. Methods: We investigated the mechanism of NUPR1 nuclear translocation involving karyopherin β1 (KPNB1), us...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Park, Chanhee, Oh, Jiwon, Lee, Won Mo, Koh, Hye Ran, Sohn, Uy Dong, Ham, Seung Wook, Oh, Kyungsoo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000408/
https://ncbi.nlm.nih.gov/pubmed/33801927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062794
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