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Diverse innate stimuli activate basophils through pathways involving Syk and IκB kinases
Mature basophils play critical inflammatory roles during helminthic, autoimmune, and allergic diseases through their secretion of histamine and the type 2 cytokines interleukin 4 (IL-4) and IL-13. Basophils are activated typically by allergen-mediated IgE cross-linking but also by endogenous “innate...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8000355/ https://ncbi.nlm.nih.gov/pubmed/33727419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019524118 |
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