The Basoph8 Mice Enable an Unbiased Detection and a Conditional Depletion of Basophils

Basophils are granulocytes involved in parasite immunity and allergic diseases, known for their potent secretion of type 2 cytokines. Identifying their functions has proven to be controversial due to their relative rarity and their complex lineage phenotype. Here, we show that the expression of baso...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Pellefigues, Christophe, Mehta, Palak, Prout, Melanie Sarah, Naidoo, Karmella, Yumnam, Bibek, Chandler, Jodie, Chappell, Sally, Filbey, Kara, Camberis, Mali, Le Gros, Graham
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746837/
https://ncbi.nlm.nih.gov/pubmed/31552058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02143
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