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Antibodies and IL-3 support helminth-induced basophil expansion

Basophils are powerful mediators of Th2 immunity and are present in increased numbers during allergic inflammation and helminth infection. Despite their ability to potentiate Th2 immunity the mechanisms regulating basophil development remain largely unknown. We have found a unique role for isotype-s...

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Detalhes bibliográficos
Principais autores: Herbst, Tina, Esser, Julia, Prati, Moira, Kulagin, Manuel, Stettler, Rebecca, Zaiss, Mario M., Hewitson, James P., Merky, Patrick, Verbeek, Joseph S., Bourquin, Carole, Camberis, Mali, Prout, Melanie, Maizels, Rick M., Le Gros, Graham, Harris, Nicola L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443190/
https://ncbi.nlm.nih.gov/pubmed/22930820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117584109
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