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Basophils are the Major Producers of IL-4 During Primary Helminth Infection

IL-4 production by leukocytes is a key regulatory event that occurs early in the type-2 immune response, which induces allergic reactions and mediates expulsion of parasites. CD4(+) T-cells and basophils are thought to be the key cell types that produce IL-4 during a type-2 response. Here, we assess...

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Bibliographische Detailangaben
Hauptverfasser: van Panhuys, Nicholas, Prout, Melanie, Forbes, Elizabeth, Min, Booki, Paul, William E, Le Gros, Graham
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488853/
https://ncbi.nlm.nih.gov/pubmed/21270410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000940
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