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Identifying Regulatory Pathways of SYK Expression in Human Basophils

BACKGROUND: Expression levels of SYK, a critical signaling tyrosine kinase in basophils, are uniquely low relative to all other circulating leukocytes and levels are highly variable in the population. HYPOTHESIS: Transcriptional regulation of SYK through unique silencing of the SYK gene determines i...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Peng, Xia, Zhao, Mingming, Gao, Li, Sen, Ranjan, MacGlashan, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062573/
https://ncbi.nlm.nih.gov/pubmed/31629804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.10.005
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