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Structural basis for selective AMPylation of Rac-subfamily GTPases by Bartonella effector protein 1 (Bep1)

Small GTPases of the Ras-homology (Rho) family are conserved molecular switches that control fundamental cellular activities in eukaryotic cells. As such, they are targeted by numerous bacterial toxins and effector proteins, which have been intensively investigated regarding their biochemical activi...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Dietz, Nikolaus, Huber, Markus, Sorg, Isabel, Goepfert, Arnaud, Harms, Alexander, Schirmer, Tilman, Dehio, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000347/
https://ncbi.nlm.nih.gov/pubmed/33723071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023245118
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