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Structural basis for selective AMPylation of Rac-subfamily GTPases by Bartonella effector protein 1 (Bep1)

Small GTPases of the Ras-homology (Rho) family are conserved molecular switches that control fundamental cellular activities in eukaryotic cells. As such, they are targeted by numerous bacterial toxins and effector proteins, which have been intensively investigated regarding their biochemical activi...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Dietz, Nikolaus, Huber, Markus, Sorg, Isabel, Goepfert, Arnaud, Harms, Alexander, Schirmer, Tilman, Dehio, Christoph
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000347/
https://ncbi.nlm.nih.gov/pubmed/33723071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023245118
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