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Structural basis for selective AMPylation of Rac-subfamily GTPases by Bartonella effector protein 1 (Bep1)

Small GTPases of the Ras-homology (Rho) family are conserved molecular switches that control fundamental cellular activities in eukaryotic cells. As such, they are targeted by numerous bacterial toxins and effector proteins, which have been intensively investigated regarding their biochemical activi...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Dietz, Nikolaus, Huber, Markus, Sorg, Isabel, Goepfert, Arnaud, Harms, Alexander, Schirmer, Tilman, Dehio, Christoph
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000347/
https://ncbi.nlm.nih.gov/pubmed/33723071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023245118
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