Llwytho...

Mechanistic basis for ubiquitin modulation of a protein energy landscape

Ubiquitin is a common posttranslational modification canonically associated with targeting proteins to the 26S proteasome for degradation and also plays a role in numerous other nondegradative cellular processes. Ubiquitination at certain sites destabilizes the substrate protein, with consequences f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Carroll, Emma C., Latorraca, Naomi R., Lindner, Johanna M., Maguire, Brendan C., Pelton, Jeffrey G., Marqusee, Susan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000280/
https://ncbi.nlm.nih.gov/pubmed/33723075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025126118
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!