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Mechanistic basis for ubiquitin modulation of a protein energy landscape
Ubiquitin is a common posttranslational modification canonically associated with targeting proteins to the 26S proteasome for degradation and also plays a role in numerous other nondegradative cellular processes. Ubiquitination at certain sites destabilizes the substrate protein, with consequences f...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8000280/ https://ncbi.nlm.nih.gov/pubmed/33723075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025126118 |
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