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A switch from noncanonical to canonical Wnt signaling stops neuroblast migration through a Slt–Robo and RGA-9b/ARHGAP–dependent mechanism

Members of the Wnt family of secreted glycoproteins regulate cell migration through distinct canonical and noncanonical signaling pathways. Studies of vertebrate development and disease have shown that these pathways can have opposing effects on cell migration, but the mechanism of this functional i...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rella, Lorenzo, Fernandes Póvoa, Euclides E., Mars, Jonas, Ebbing, Annabel L. P., Schoppink, Luc, Betist, Marco C., Korswagen, Hendrik C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000201/
https://ncbi.nlm.nih.gov/pubmed/33737394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013239118
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