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Proximal Tubular Vacuolization and Hypersensitivity to Drug-Induced Nephrotoxicity in Male Mice With Decreased Expression of the NADPH-Cytochrome P450 Reductase

The effect of variations in the expression of cytochrome P450 reductase (CPR or POR) is determined in mice with decreased POR expression to identify potential vulnerabilities in people with low POR expression. There is an age-dependent appearance of increasing vacuolization in the proximal tubules o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Toxicol Sci
मुख्य लेखकों: Ding, Liang, Li, Lei, Liu, Senyan, Bao, Xiaochen, Dickman, Kathleen G, Sell, Stewart S, Mei, Changlin, Zhang, Qing-Yu, Gu, Jun, Ding, Xinxin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000068/
https://ncbi.nlm.nih.gov/pubmed/31693140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz225
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