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Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows a Strong Prognostic Value in Triple Negative Breast Cancer Patients

SIMPLE SUMMARY: The use of BRD4 inhibitors has emerged as a novel therapeutic approach in a wide variety of tumors including the triple negative breast cancer. Moreover, PP2A has been proposed as the phosphatase involved in regulating BRD4 phosphorylation and stabilization. Our aim was to evaluate f...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sanz-Álvarez, Marta, Cristóbal, Ion, Luque, Melani, Santos, Andrea, Zazo, Sandra, Madoz-Gúrpide, Juan, Caramés, Cristina, Chiang, Cheng-Ming, García-Foncillas, Jesús, Eroles, Pilar, Albanell, Joan, Rojo, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999847/
https://ncbi.nlm.nih.gov/pubmed/33809005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061246
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