Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows a Strong Prognostic Value in Triple Negative Breast Cancer Patients

SIMPLE SUMMARY: The use of BRD4 inhibitors has emerged as a novel therapeutic approach in a wide variety of tumors including the triple negative breast cancer. Moreover, PP2A has been proposed as the phosphatase involved in regulating BRD4 phosphorylation and stabilization. Our aim was to evaluate f...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Sanz-Álvarez, Marta, Cristóbal, Ion, Luque, Melani, Santos, Andrea, Zazo, Sandra, Madoz-Gúrpide, Juan, Caramés, Cristina, Chiang, Cheng-Ming, García-Foncillas, Jesús, Eroles, Pilar, Albanell, Joan, Rojo, Federico
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999847/
https://ncbi.nlm.nih.gov/pubmed/33809005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061246
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