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Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity

Although epoxyeicosatrienoic acid (EET) analogs have performed well in several acute and chronic kidney disease models, targeted delivery of EET analogs to the kidney can be reasonably expected to reduce the level of drug needed to achieve a therapeutic effect and obviate possible side effects. For...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Imig, John D., Hye Khan, Md Abdul, Burkhan, Anna, Chen, Guan, Adebesin, Adeniyi Michael, Falck, John R.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998941/
https://ncbi.nlm.nih.gov/pubmed/33801911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062793
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