Epoxyeicosatrienoic Acid Analog Decreases Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition

Renal fibrosis, which is a critical pathophysiological event in chronic kidney diseases, is associated with renal epithelial-to-mesenchymal transition (EMT). Epoxyeicosatrienoic acids (EETs) are Cyp epoxygenase arachidonic acid metabolites that demonstrate biological actions that result in kidney pr...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Skibba, Melissa, Hye Khan, Md. Abdul, Kolb, Lauren L., Yeboah, Michael M., Falck, John R., Amaradhi, Radhika, Imig, John D.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491687/
https://ncbi.nlm.nih.gov/pubmed/28713267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00406
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