Role of the cytochrome P-450/ epoxyeicosatrienoic acids pathway in the pathogenesis of renal dysfunction in cirrhosis

BACKGROUND: Hepatorenal syndrome (HRS) is a life-threatening complication of advanced liver cirrhosis that is characterized by hemodynamic alterations in the kidney and other vascular beds. Cytochrome P(CYP)-450 enzymes metabolize arachidonic acid to epoxyeicosatrienoic acids (EETs) and 20-hydroxyei...

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Bibliografiska uppgifter
I publikationen:Nephrol Dial Transplant
Huvudupphovsmän: Yeboah, Michael M, Hye Khan, Md Abdul, Chesnik, Marla A, Skibba, Melissa, Kolb, Lauren L, Imig, John D
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
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ORIGINAL ARTICLES
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070028/
https://ncbi.nlm.nih.gov/pubmed/29361048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfx354
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