The Phosphorylation Status of Drp1-Ser637 by PKA in Mitochondrial Fission Modulates Mitophagy via PINK1/Parkin to Exert Multipolar Spindles Assembly during Mitosis

Mitochondrial fission and fusion cycles are integrated with cell cycle progression. Here we first re-visited how mitochondrial ETC inhibition disturbed mitosis progression, resulting in multipolar spindles formation in HeLa cells. Inhibitors of ETC complex I (rotenone, ROT) and complex III (antimyci...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Ko, Huey-Jiun, Tsai, Cheng-Yu, Chiou, Shean-Jaw, Lai, Yun-Ling, Wang, Chi-Huei, Cheng, Jiin-Tsuey, Chuang, Tsung-Hsien, Huang, Chi-Ying F., Kwan, Aij-Lie, Loh, Joon-Khim, Hong, Yi-Ren
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998912/
https://ncbi.nlm.nih.gov/pubmed/33805672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11030424
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