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Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives

The genome of the human intracellular pathogen Mycobacterium tuberculosis encodes an unusually large number of epoxide hydrolases, which are thought to be involved in lipid metabolism and detoxification reactions needed to endure the hostile environment of host macrophages. These enzymes therefore r...

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Pubblicato in:Int J Mol Sci
Autori principali: Madacki, Jan, Kopál, Martin, Jackson, Mary, Korduláková, Jana
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998700/
https://ncbi.nlm.nih.gov/pubmed/33809178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062884
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