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Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives

The genome of the human intracellular pathogen Mycobacterium tuberculosis encodes an unusually large number of epoxide hydrolases, which are thought to be involved in lipid metabolism and detoxification reactions needed to endure the hostile environment of host macrophages. These enzymes therefore r...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Madacki, Jan, Kopál, Martin, Jackson, Mary, Korduláková, Jana
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998700/
https://ncbi.nlm.nih.gov/pubmed/33809178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062884
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