Immunogenic Cell Death by the Novel Topoisomerase I Inhibitor TLC388 Enhances the Therapeutic Efficacy of Radiotherapy

SIMPLE SUMMARY: This study aims to evaluate the induction of immunogenic cell death (ICD) for anticancer immunity by the novel topoisomerase I inhibitor lipotecan. These results show that lipotecan can remarkably elicit ICD and increase tumor immunogenicity, which promotes the therapeutic efficacy o...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Huang, Kevin Chih-Yang, Chiang, Shu-Fen, Yang, Pei-Chen, Ke, Tao-Wei, Chen, Tsung-Wei, Hu, Ching-Han, Huang, Yi-Wen, Chang, Hsin-Yu, Chen, William Tzu-Liang, Chao, K. S. Clifford
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998596/
https://ncbi.nlm.nih.gov/pubmed/33799527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061218
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