Clinical significance of programmed death 1 ligand-1 (CD274/PD-L1) and intra-tumoral CD8+ T-cell infiltration in stage II–III colorectal cancer

Programmed cell death-1 (PDCD1/PD-1) and its ligand programmed cell death 1 ligand 1 (CD274/PD-L1) have been reported to suppress anti-tumor T cell-mediated immune responses. However, the clinical significance of CD274 in colorectal cancer were still elusive. We aim to clarify the relationships betw...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Chih-Yang, Chiang, Shu-Fen, Ke, Tao-Wei, Chen, Tsung-Wei, You, Ying-Shu, Chen, William Tzu-Liang, Chao, K. S. Clifford
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199287/
https://ncbi.nlm.nih.gov/pubmed/30353144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33927-5
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