IFNAR1 signaling in NK cells promotes persistent virus infection

Inhibition of type 1 interferon (IFN-I) signaling promotes the control of persistent virus infection, but the underlying mechanisms remain poorly understood. Here, we report that genetic ablation of Ifnar1 specifically in natural killer (NK) cells led to elevated numbers of T follicular helper cells...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Huang, Zhe, Kang, Seung Goo, Li, Yunqiao, Zak, Jaroslav, Shaabani, Namir, Deng, Kaiyuan, Shepherd, Jovan, Bhargava, Raag, Teijaro, John R., Xiao, Changchun
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997497/
https://ncbi.nlm.nih.gov/pubmed/33771858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb8087
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