IFNAR1 signaling in NK cells promotes persistent virus infection

Inhibition of type 1 interferon (IFN-I) signaling promotes the control of persistent virus infection, but the underlying mechanisms remain poorly understood. Here, we report that genetic ablation of Ifnar1 specifically in natural killer (NK) cells led to elevated numbers of T follicular helper cells...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Huang, Zhe, Kang, Seung Goo, Li, Yunqiao, Zak, Jaroslav, Shaabani, Namir, Deng, Kaiyuan, Shepherd, Jovan, Bhargava, Raag, Teijaro, John R., Xiao, Changchun
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997497/
https://ncbi.nlm.nih.gov/pubmed/33771858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb8087
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