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The herpesvirus accessory protein γ(1)34.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I
RIG-I and MDA5 are cytoplasmic RNA sensors that mediate cell intrinsic immunity against viral pathogens. While it has been well-established that RIG-I and MDA5 recognize RNA viruses, their interactive network with DNA viruses, including herpes simplex virus 1 (HSV-1), remains less clear. Using a com...
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| Udgivet i: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7996975/ https://ncbi.nlm.nih.gov/pubmed/33770145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009446 |
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