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Rescue of Infectious Rotavirus Reassortants by a Reverse Genetics System Is Restricted by the Receptor-Binding Region of VP4

The rotavirus species A (RVA) capsid contains the spike protein VP4, which interacts with VP6 and VP7 and is involved in cellular receptor binding. The capsid encloses the genome consisting of eleven dsRNA segments. Reassortment events can result in novel strains with changed properties. Using a pla...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Falkenhagen, Alexander, Huyzers, Marno, van Dijk, Alberdina A., Johne, Reimar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996497/
https://ncbi.nlm.nih.gov/pubmed/33668972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13030363
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