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Rescue of Infectious Rotavirus Reassortants by a Reverse Genetics System Is Restricted by the Receptor-Binding Region of VP4

The rotavirus species A (RVA) capsid contains the spike protein VP4, which interacts with VP6 and VP7 and is involved in cellular receptor binding. The capsid encloses the genome consisting of eleven dsRNA segments. Reassortment events can result in novel strains with changed properties. Using a pla...

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Bibliographic Details
Published in:Viruses
Main Authors: Falkenhagen, Alexander, Huyzers, Marno, van Dijk, Alberdina A., Johne, Reimar
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996497/
https://ncbi.nlm.nih.gov/pubmed/33668972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13030363
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