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Generation of Simian Rotavirus Reassortants with VP4- and VP7-Encoding Genome Segments from Human Strains Circulating in Africa Using Reverse Genetics

Human rotavirus A (RVA) causes acute gastroenteritis in infants and young children. The broad use of two vaccines, which are based on RVA strains from Europe and North America, significantly reduced rotavirus disease burden worldwide. However, a lower vaccine effectiveness is recorded in some region...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Falkenhagen, Alexander, Patzina-Mehling, Corinna, Gadicherla, Ashish K., Strydom, Amy, O’Neill, Hester G., Johne, Reimar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077283/
https://ncbi.nlm.nih.gov/pubmed/32054092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12020201
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