Generation of Simian Rotavirus Reassortants with VP4- and VP7-Encoding Genome Segments from Human Strains Circulating in Africa Using Reverse Genetics

Human rotavirus A (RVA) causes acute gastroenteritis in infants and young children. The broad use of two vaccines, which are based on RVA strains from Europe and North America, significantly reduced rotavirus disease burden worldwide. However, a lower vaccine effectiveness is recorded in some region...

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Publicat a:Viruses
Autors principals: Falkenhagen, Alexander, Patzina-Mehling, Corinna, Gadicherla, Ashish K., Strydom, Amy, O’Neill, Hester G., Johne, Reimar
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077283/
https://ncbi.nlm.nih.gov/pubmed/32054092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12020201
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