A novel machine learning approach (svmSomatic) to distinguish somatic and germline mutations using next-generation sequencing data

Somatic mutations are a large category of genetic variations, which play an essential role in tumorigenesis. Detection of somatic single nucleotide variants (SNVs) could facilitate downstream analysis of tumorigenesis. Many computational methods have been developed to detect SNVs, but most require n...

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Bibliographic Details
Published in:Zool Res
Main Authors: Mao, Yu-Fang, Yuan, Xi-Guo, Cun, Yu-Peng
Format: Artigo
Language:Inglês
Published: Science Press 2021
Subjects:
Letters to the Editor
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995270/
https://ncbi.nlm.nih.gov/pubmed/33709636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.24272/j.issn.2095-8137.2021.014
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