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BOK controls apoptosis by Ca(2+) transfer through ER-mitochondrial contact sites
Calcium transfer from the endoplasmic reticulum (ER) to mitochondria is a critical contributor to apoptosis. B cell lymphoma 2 (BCL-2) ovarian killer (BOK) localizes to the ER and binds the inositol 1,4,5-trisphosophate receptor (IP3R). Here, we show that BOK is necessary for baseline mitochondrial...
Gorde:
| Argitaratua izan da: | Cell Rep |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7995216/ https://ncbi.nlm.nih.gov/pubmed/33691099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108827 |
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