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An in silico analysis of effective siRNAs against COVID‐19 by targeting the leader sequence of SARS‐CoV‐2

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is a retrovirus having genome size of around 30 kb. Its genome contains a highly conserved leader sequence at its 5′ end, which is added to all subgenomic mRNAs at their 5′ terminus by a discontinuous transcription mechanism and regulates...

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Vydáno v:Adv Cell Gene Ther
Hlavní autoři: Pandey, Anand Kumar, Verma, Shalja
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995175/
https://ncbi.nlm.nih.gov/pubmed/33786418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acg2.107
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