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Factual insights of the allosteric inhibition mechanism of SARS-CoV-2 main protease by quercetin: an in silico analysis
SARS-CoV-2 main protease (M(pro)) cleaves the viral polypeptide 1a and 1ab in a site-specific ((L-Q|(S, A, G)) manner and produce functional enzymes for mediating viral replication. Numerous studies have reported synthetic competitive inhibitors against this target enzyme but increase in substrate c...
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| Publicado no: | 3 Biotech |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7802979/ https://ncbi.nlm.nih.gov/pubmed/33457176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-020-02630-6 |
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