siRNA targeting the Leader sequence of SARS-CoV inhibits virus replication

SARS-CoV (the SARS-Associated Coronavirus) was reported as a novel virus member in the coronavirus family, which was the cause of severe acute respiratory syndrome. Coronavirus replication occurs through a unique mechanism employing Leader sequence in the transcripts when initiating transcription fr...

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Publicado no:Gene Ther
Main Authors: Li, T, Zhang, Y, Fu, L, Yu, C, Li, X, Li, Y, Zhang, X, Rong, Z, Wang, Y, Ning, H, Liang, R, Chen, W, Babiuk, L A, Chang, Z
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091583/
https://ncbi.nlm.nih.gov/pubmed/15772689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3302479
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