Drug Repurposing of Itraconazole and Estradiol Benzoate against COVID‐19 by Blocking SARS‐CoV‐2 Spike Protein‐Mediated Membrane Fusion

SARS‐CoV‐2 caused the emerging epidemic of coronavirus disease in 2019 (COVID‐19). To date, there are more than 82.9 million confirmed cases worldwide, there is no clinically effective drug against SARS‐CoV‐2 infection. The conserved properties of the membrane fusion domain of the spike (S) protein...

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Dettagli Bibliografici
Pubblicato in:Adv Ther (Weinh)
Autori principali: Yang, Chan, Pan, Xiaoyan, Huang, Yuan, Cheng, Chen, Xu, Xinfeng, Wu, Yan, Xu, Yunxia, Shang, Weijuan, Niu, Xiaoge, Wan, Yihong, Li, Zhaofeng, Zhang, Rong, Liu, Shuwen, Xiao, Gengfu, Xu, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994988/
https://ncbi.nlm.nih.gov/pubmed/33786369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adtp.202000224
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