Drug Repurposing of Itraconazole and Estradiol Benzoate against COVID‐19 by Blocking SARS‐CoV‐2 Spike Protein‐Mediated Membrane Fusion

SARS‐CoV‐2 caused the emerging epidemic of coronavirus disease in 2019 (COVID‐19). To date, there are more than 82.9 million confirmed cases worldwide, there is no clinically effective drug against SARS‐CoV‐2 infection. The conserved properties of the membrane fusion domain of the spike (S) protein...

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Bibliografiske detaljer
Udgivet i:Adv Ther (Weinh)
Main Authors: Yang, Chan, Pan, Xiaoyan, Huang, Yuan, Cheng, Chen, Xu, Xinfeng, Wu, Yan, Xu, Yunxia, Shang, Weijuan, Niu, Xiaoge, Wan, Yihong, Li, Zhaofeng, Zhang, Rong, Liu, Shuwen, Xiao, Gengfu, Xu, Wei
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
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Full Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994988/
https://ncbi.nlm.nih.gov/pubmed/33786369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adtp.202000224
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