Repurposing itraconazole as an anticancer agent

Itraconazole, a common anti-fungal agent, has demonstrated potential anticancer activity, including reversing chemoresistance mediated by P-glycoprotein, modulating the signal transduction pathways of Hedgehog, mechanistic target of rapamycin and Wnt/β-catenin in cancer cells, inhibiting angiogenesi...

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Detalles Bibliográficos
Publicado en:Oncol Lett
Main Authors: Tsubamoto, Hiroshi, Ueda, Tomoko, Inoue, Kayo, Sakata, Kazuko, Shibahara, Hiroaki, Sonoda, Takashi
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2017
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529765/
https://ncbi.nlm.nih.gov/pubmed/28789339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6325
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